Epidermal Grafts for Vitiligo

Some success has been achieved by using the epidermal grafting for the treatment of stable vitiligo and peibaldism but there is a variation in the result in case of progressive vitiligo. 26 patients having stable vitiligo and 14 patients of progressive vitiligo have been examined in this study held in South Korea after an observation of three months who pass through the epidermal grafting.

Suction of 250 mm Hg for two to three hours was applied to the donor sites to create epidermal bullae and to place them on the recipient sites they were harvested. With the help of suction machine, these recipient sites were set ready. In 38 patients and in two patients liquid nitrogen was used for the purpose.  Patients were followed for around 3 to thirty months and adjuvant phototherapy was also not given to them.

73% of the patients having stable vitiligo achieved repigmentation more than 95% and the same ratio of repigmentation was in 71% of the progressive vitiligo patients. Depigmentation occurred again in the 10% of the patients having stable vitiligo and in 40% of the patients having progressive vitiligo after three months. 10% to 95% (partial repigmentation) took place in 19% of the patients having stable vitiligo and in 21% of the patients with progressive vitiligo disease. In two patient’s donor sites, koebner phenomenon was developed with natural repigmentation after around 1 to 2 years.

Resource:

Healthguidances.com

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22 December

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